Depressive Symptoms, Pain, Chronic Medical Morbidity, and Interleukin-6 among Primary Care Patients

Interleukin-6, cortisol, and depressive symptoms in ovarian cancer patients.

PURPOSE Inflammatory processes have been implicated in the pathogenesis of both depression and cancer. Links between depressive symptoms, interleukin-6 (IL-6), and cortisol dysregulation have been demonstrated in cancer patients, but vegetative versus affective components of depression have been minimally examined. The objective of the current study was to examine associations between IL-6, diu...

Depressive Symptoms, Pain, and Quality of Life among Patients with Nonalcohol-Related Chronic Pancreatitis

Objective. The present study was conducted to determine if depressive symptoms were associated with variability in pain perception and quality of life among patients with nonalcohol-related chronic pancreatitis. Methods. The research design was cross-sectional, and self-report data was collected from 692 patients with nonalcohol-related, intractable pancreatitis. The mean age of the sample was ...

Primary care for chronic pain patients.

Serotonin transporter gene, depressive symptoms, and interleukin-6.

BACKGROUND We explored the relationship of genetic variants of the serotonin transporter gene SLC6A4, a key regulator of the serotonergic neurotransmission, with both depressive symptoms and plasma interleukin-6 (IL-6) levels. METHODS AND RESULTS We genotyped 20 polymorphisms in 360 male twins (mean age, 54 years) from the Vietnam Era Twin Registry. Current depressive symptoms were measured w...

Comparing the co morbidity of psychological disorder among women and men with chronic musculoskeletal pain

Introduction: Chronic pain is one of the most common reasons for referring to elderly medical centers. About 20 -25 percent of patients with chronic pain experience significant psychological symptoms. The current study was designed to evaluate the prevalence of depression, anxiety in patients with chronic musculoskeletal pain referred to pain clinic of Imam Hossein hospital. Methods: In ...